Cargando…
Characterization of Glycosylation-Specific Systemic and Mucosal IgA Antibody Responses to Escherichia coli Mucinase YghJ (SslE)
Efforts to develop broadly protective vaccines against pathogenic Escherichia coli are ongoing. A potential antigen candidate for vaccine development is the metalloprotease YghJ, or SslE. YghJ is a conserved mucinase that is immunogenic, heavily glycosylated, and produced by most pathogenic E. coli....
Autores principales: | Riaz, Saman, Steinsland, Hans, Thorsing, Mette, Andersen, Ann Z., Boysen, Anders, Hanevik, Kurt |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718676/ https://www.ncbi.nlm.nih.gov/pubmed/34975849 http://dx.doi.org/10.3389/fimmu.2021.760135 |
Ejemplares similares
-
Linking inherent O-Linked Protein Glycosylation of YghJ to Increased Antigen Potential
por: Thorsing, Mette, et al.
Publicado: (2021) -
Pathogenic E. coli Exploits SslE Mucinase Activity to Translocate through the Mucosal Barrier and Get Access to Host Cells
por: Valeri, Maria, et al.
Publicado: (2015) -
SslE Elicits Functional Antibodies That Impair In Vitro Mucinase Activity and In Vivo Colonization by Both Intestinal and Extraintestinal Escherichia coli Strains
por: Nesta, Barbara, et al.
Publicado: (2014) -
M60-like metalloprotease domain of the Escherichia coli YghJ protein forms amyloid fibrils
por: Belousov, Mikhail V., et al.
Publicado: (2018) -
Correction: SslE Elicits Functional Antibodies That Impair In Vitro Mucinase Activity and In Vivo Colonization by Both Intestinal and Extraintestinal Escherichia coli Strains
Publicado: (2015)