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Adults with Plasmodium falciparum malaria have higher magnitude and quality of circulating T-follicular helper cells compared to children

BACKGROUND: Protective malarial antibodies are acquired more rapidly in adults than children, independently of cumulative exposure, however the cellular responses mediating these differences are unknown. CD4 T-follicular helper (Tfh) cells have key roles in inducing antibodies, with Th2-Tfh cell act...

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Detalles Bibliográficos
Autores principales: Oyong, Damian. A., Loughland, Jessica. R., Soon, Megan. S.F., Chan, Jo-Anne, Andrew, Dean, Wines, Bruce D., Hogarth, P. Mark, Olver, Stuart D., Collinge, Alika D., Varelias, Antiopi, Beeson, James G., Kenangalem, Enny, Price, Ric N., Anstey, Nicholas M., Minigo, Gabriela, Boyle, Michelle J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718734/
https://www.ncbi.nlm.nih.gov/pubmed/34968760
http://dx.doi.org/10.1016/j.ebiom.2021.103784