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Molecular Dissection of the Primase and Polymerase Activities of Deep-Sea Phage NrS-1 Primase-Polymerase

PrimPols are a class of primases that belong to the archaeo-eukaryotic primase (AEP) superfamily but have both primase and DNA polymerase activities. Replicative polymerase from NrS-1 phage (NrSPol) is a representative of the PrimPols. In this study, we identified key residues for the catalytic acti...

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Detalles Bibliográficos
Autores principales: Huang, Fengtao, Lu, Xueling, Yu, Chunxiao, Sliz, Piotr, Wang, Longfei, Zhu, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718748/
https://www.ncbi.nlm.nih.gov/pubmed/34975792
http://dx.doi.org/10.3389/fmicb.2021.766612