Cargando…

Molecular Dissection of the Primase and Polymerase Activities of Deep-Sea Phage NrS-1 Primase-Polymerase

PrimPols are a class of primases that belong to the archaeo-eukaryotic primase (AEP) superfamily but have both primase and DNA polymerase activities. Replicative polymerase from NrS-1 phage (NrSPol) is a representative of the PrimPols. In this study, we identified key residues for the catalytic acti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Fengtao, Lu, Xueling, Yu, Chunxiao, Sliz, Piotr, Wang, Longfei, Zhu, Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718748/ https://www.ncbi.nlm.nih.gov/pubmed/34975792 http://dx.doi.org/10.3389/fmicb.2021.766612

Ejemplares similares

Corrigendum: Molecular Dissection of the Primase and Polymerase Activities of Deep-Sea Phage NrS-1 Primase-Polymerase
por: Huang, Fengtao, et al.
Publicado: (2022)

Structural studies reveal a ring-shaped architecture of deep-sea vent phage NrS-1 polymerase
por: Chen, Xi, et al.
Publicado: (2020)

PrimPol, an Archaic Primase/Polymerase Operating in Human Cells
por: García-Gómez, Sara, et al.
Publicado: (2013)

The DNA Polymerase ʱ-Primase Complex: Multiple Functions and Interactions
por: Muzi-Falconi, Marco, et al.
Publicado: (2003)

Primase-polymerases: how to make a primer from scratch
por: Bainbridge, Lewis J., et al.
Publicado: (2023)

Primase-polymerases are a functionally diverse superfamily of replication and repair enzymes
por: Guilliam, Thomas A., et al.
Publicado: (2015)

DNA Damage Tolerance by Eukaryotic DNA Polymerase and Primase PrimPol
por: Boldinova, Elizaveta O., et al.
Publicado: (2017)

CRISPR-Associated Primase-Polymerases are implicated in prokaryotic CRISPR-Cas adaptation
por: Zabrady, Katerina, et al.
Publicado: (2021)

Optimal numbers of residues in linkers of DNA polymerase I, T7 primase and DNA polymerase IV
por: Fu, Yi-Ben, et al.
Publicado: (2016)

Structure and mechanism of human PrimPol, a DNA polymerase with primase activity
por: Rechkoblit, Olga, et al.
Publicado: (2016)

Engineering human PrimPol into an efficient RNA-dependent-DNA primase/polymerase
por: Agudo, Rubén, et al.
Publicado: (2017)

Molecular basis for DNA repair synthesis on short gaps by mycobacterial Primase-Polymerase C
por: Brissett, Nigel C., et al.
Publicado: (2020)

CST–Polymeraseα-primase solves a second telomere end-replication problem
por: Takai, Hiro, et al.
Publicado: (2023)

Stringent Primer Termination by an Archaeo-Eukaryotic DNA Primase
por: Bergsch, Jan, et al.
Publicado: (2021)

Functional interplay of DnaE polymerase, DnaG primase and DnaC helicase within a ternary complex, and primase to polymerase hand-off during lagging strand DNA replication in Bacillus subtilis
por: Rannou, Olivier, et al.
Publicado: (2013)

Primase is required for helicase activity and helicase alters the specificity of primase in the enteropathogen Clostridium difficile
por: van Eijk, Erika, et al.
Publicado: (2016)

Structural basis of DNA synthesis opposite 8-oxoguanine by human PrimPol primase-polymerase
por: Rechkoblit, Olga, et al.
Publicado: (2021)

Flexibility and distributive synthesis regulate RNA priming and handoff in human DNA polymerase α-primase
por: Cordoba, John J., et al.
Publicado: (2023)

A Conserved Motif in the C-terminal Tail of DNA Polymerase α Tethers Primase to the Eukaryotic Replisome
por: Kilkenny, Mairi L., et al.
Publicado: (2012)

Mimivirus encodes a multifunctional primase with DNA/RNA polymerase, terminal transferase and translesion synthesis activities
por: Gupta, Ankita, et al.
Publicado: (2019)

Mobile genetic element-encoded putative DNA primases composed of A-family polymerase—SSB pairs
por: Rice, Phoebe A.
Publicado: (2023)

Deletion of the primase-polymerases encoding gene, located in a mobile element in Thermus thermophilus HB27, leads to loss of function mutation of addAB genes
por: Verdú, Carlos, et al.
Publicado: (2022)

Klebsiella Phage KP34 RNA Polymerase and Its Use in RNA Synthesis
por: Lu, Xueling, et al.
Publicado: (2019)

Primase-based whole genome amplification
por: Li, Ying, et al.
Publicado: (2008)

Identification of Amino Acids Essential for Viral Replication in the HCMV Helicase-Primase Complex
por: Ligat, Gaetan, et al.
Publicado: (2018)

Residues located in the primase domain of the bacteriophage T7 primase-helicase are essential for loading the hexameric complex onto DNA
por: Hernandez, Alfredo J., et al.
Publicado: (2022)

The monomeric archaeal primase from Nanoarchaeum equitans harbours the features of heterodimeric archaeoeukaryotic primases and primes sequence-specifically
por: Schneider, Andy, et al.
Publicado: (2023)

A thermostable DNA primase‐polymerase from a mobile genetic element involved in defence against environmental DNA
por: García‐Quintans, Nieves, et al.
Publicado: (2020)

Structural basis for the interaction of SARS‐CoV‐2 virulence factor nsp1 with DNA polymerase α–primase
por: Kilkenny, Mairi L., et al.
Publicado: (2021)

The combined DNA and RNA synthetic capabilities of archaeal DNA primase facilitate primer hand-off to the replicative DNA polymerase
por: Greci, Mark D., et al.
Publicado: (2022)

DNA polymerase D temporarily connects primase to the CMG-like helicase before interacting with proliferating cell nuclear antigen
por: Oki, Keisuke, et al.
Publicado: (2021)

Yeast require redox switching in DNA primase
por: O’Brien, Elizabeth, et al.
Publicado: (2018)

The Mini-Chromosome Maintenance (Mcm) Complexes Interact with DNA Polymerase α-Primase and Stimulate Its Ability to Synthesize RNA Primers
por: You, Zhiying, et al.
Publicado: (2013)

Plant organellar DNA primase-helicase synthesizes RNA primers for organellar DNA polymerases using a unique recognition sequence
por: Peralta-Castro, Antolín, et al.
Publicado: (2017)

E. coli primase and DNA polymerase III holoenzyme are able to bind concurrently to a primed template during DNA replication
por: Bogutzki, Andrea, et al.
Publicado: (2019)

A novel non-radioactive primase–pyrophosphatase activity assay and its application to the discovery of inhibitors of Mycobacterium tuberculosis primase DnaG
por: Biswas, Tapan, et al.
Publicado: (2013)

UL52 Primase Interactions in the Herpes Simplex Virus 1 Helicase-Primase Are Affected by Antiviral Compounds and Mutations Causing Drug Resistance
por: Muylaert, Isabella, et al.
Publicado: (2014)

Molecular choreography of primer synthesis by the eukaryotic Pol α-primase
por: Yuan, Zuanning, et al.
Publicado: (2023)

Molecular choreography of primer synthesis by the eukaryotic Pol α-primase
por: Yuan, Zuanning, et al.
Publicado: (2023)

Properties of an unusual DNA primase from an archaeal plasmid
por: Beck, Kirsten, et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_35c22q2iur0jh4osjg0d2mmfgp