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ITGB1 Drives Hepatocellular Carcinoma Progression by Modulating Cell Cycle Process Through PXN/YWHAZ/AKT Pathways

Integrin β1 (ITGB1), which acts as an extracellular matrix (ECM) receptor, has gained increasing attention as a therapeutic target for the treatment of hepatocellular carcinoma (HCC). However, the underpinning mechanism of how ITGB1 drives HCC progression remains elusive. In this study, we first fou...

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Detalles Bibliográficos
Autores principales: Xie, Jinghe, Guo, Tingting, Zhong, Zhiyong, Wang, Ning, Liang, Yan, Zeng, Weiping, Liu, Shoupei, Chen, Qicong, Tang, Xianglian, Wu, Haibin, Zhang, Shuai, Ma, Keqiang, Wang, Bailin, Ou, Yimeng, Gu, Weili, Chen, Honglin, Qiu, Yaqi, Duan, Yuyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718767/
https://www.ncbi.nlm.nih.gov/pubmed/34977001
http://dx.doi.org/10.3389/fcell.2021.711149