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pH-Dependent Mechanisms of Influenza Infection Mediated by Hemagglutinin

Influenza hemagglutinin (HA) is a viral membrane bound protein that plays a critical role in the viral life cycle by mediating entry into target cells. HA exploits the lowering of the pH in the endosomal compartment to initiate a series of conformational changes that promote access of the viral gene...

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Detalles Bibliográficos
Autores principales: Caffrey, Michael, Lavie, Arnon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718792/
https://www.ncbi.nlm.nih.gov/pubmed/34977156
http://dx.doi.org/10.3389/fmolb.2021.777095