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Toward efficient multiple-site incorporation of unnatural amino acids using cell-free translation system

Amber suppression has been widely used to incorporate unnatural amino acids (UNAAs) with unique structures or functional side-chain groups into specific sites of the target protein, which expands the scope of protein-coding chemistry. However, this traditional strategy does not allow multiple-site i...

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Detalles Bibliográficos
Autores principales: Hou, Jiaqi, Chen, Xinjie, Jiang, Nan, Wang, Yanan, Cui, Yi, Ma, Lianju, Lin, Ying, Lu, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718814/
https://www.ncbi.nlm.nih.gov/pubmed/35024479
http://dx.doi.org/10.1016/j.synbio.2021.12.007