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CD244 expression represents functional decline of murine hematopoietic stem cells after in vitro culture

Isolation of long-term hematopoietic stem cell (HSC) is possible by utilizing flow cytometry with multiple cell surface markers. However, those cell surface phenotypes do not represent functional HSCs after in vitro culture. Here we show that cultured HSCs express mast cell-related genes including C...

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Detalles Bibliográficos
Autores principales: Koide, Shuhei, Sigurdsson, Valgardur, Radulovic, Visnja, Saito, Kiyoka, Zheng, Zhiqian, Lang, Stefan, Soneji, Shamit, Iwama, Atsushi, Miharada, Kenichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718822/
https://www.ncbi.nlm.nih.gov/pubmed/35005548
http://dx.doi.org/10.1016/j.isci.2021.103603