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NAP1L5 Promotes Nucleolar Hypertrophy and Is Required for Translation Activation During Cardiomyocyte Hypertrophy

Pathological growth of cardiomyocytes during hypertrophy is characterized by excess protein synthesis; however, the regulatory mechanism remains largely unknown. Using a neonatal rat ventricular myocytes (NRVMs) model, here we find that the expression of nucleosome assembly protein 1 like 5 (Nap1l5)...

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Detalles Bibliográficos
Autores principales: Guo, Ningning, Zheng, Di, Sun, Jiaxin, Lv, Jian, Wang, Shun, Fang, Yu, Zhao, Zhenyi, Zeng, Sai, Guo, Qiuxiao, Tong, Jingjing, Wang, Zhihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718910/
https://www.ncbi.nlm.nih.gov/pubmed/34977198
http://dx.doi.org/10.3389/fcvm.2021.791501