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miR-29cb2 promotes angiogenesis and osteogenesis by inhibiting HIF-3α in bone
Coordination between osteogenesis and angiogenesis is required for bone homeostasis. Here, we show that miR-29cb2 is a bone-specific miRNA and plays critical roles on angiogenesis-osteogenesis coupling during bone remodeling. Mice with deletion of miR-29cb2 exhibit osteopenic phenotypes and osteobla...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718933/ https://www.ncbi.nlm.nih.gov/pubmed/35005549 http://dx.doi.org/10.1016/j.isci.2021.103604 |