miR-29cb2 promotes angiogenesis and osteogenesis by inhibiting HIF-3α in bone

Coordination between osteogenesis and angiogenesis is required for bone homeostasis. Here, we show that miR-29cb2 is a bone-specific miRNA and plays critical roles on angiogenesis-osteogenesis coupling during bone remodeling. Mice with deletion of miR-29cb2 exhibit osteopenic phenotypes and osteobla...

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Detalles Bibliográficos
Autores principales: Ouyang, Liping, Sun, Yingxiao, Lv, Dan, Peng, Xiaochun, Liu, Xiaoming, Ci, Lei, Zhang, Guoning, Yuan, Bo, Li, Ling, Fei, Jian, Ma, Jun, Liu, Xuanyong, Liao, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718933/
https://www.ncbi.nlm.nih.gov/pubmed/35005549
http://dx.doi.org/10.1016/j.isci.2021.103604

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