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Shining a light on autophagy in neurodegenerative diseases

Small-molecule modulators of autophagy have been widely investigated as potential therapies for neurodegenerative diseases. In a recent issue of JBC, Safren et al. described a novel assay that uses a photoconvertible fusion protein to identify compounds that alter autophagic flux. Autophagy inducers...

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Detalles Bibliográficos
Autores principales: Chandran, Aswathy, Rochet, Jean-Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718947/
https://www.ncbi.nlm.nih.gov/pubmed/34801556
http://dx.doi.org/10.1016/j.jbc.2021.101437