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Physiopathological Relevance of D-Serine in the Mammalian Cochlea

NMDA receptors (NMDARs) populate the complex between inner hair cell (IHC) and spiral ganglion neurons (SGNs) in the developing and mature cochlea. However, in the mature cochlea, activation of NMDARs is thought to mainly occur under pathological conditions such as excitotoxicity. Ototoxic drugs suc...

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Detalles Bibliográficos
Autores principales: Wang, Jing, Serratrice, Nicolas, Lee, Cindy J., François, Florence, Sweedler, Jonathan V., Puel, Jean-Luc, Mothet, Jean-Pierre, Ruel, Jérôme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718999/
https://www.ncbi.nlm.nih.gov/pubmed/34975405
http://dx.doi.org/10.3389/fncel.2021.733004