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Kir6.2-deficient mice develop somatosensory dysfunction and axonal loss in the peripheral nerves
Glucose-responsive ATP-sensitive potassium channels (K(ATP)) are expressed in a variety of tissues including nervous systems. The depolarization of the membrane potential induced by glucose may lead to hyperexcitability of neurons and induce excitotoxicity. However, the roles of K(ATP) in the periph...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719014/ https://www.ncbi.nlm.nih.gov/pubmed/35005553 http://dx.doi.org/10.1016/j.isci.2021.103609 |