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Kir6.2-deficient mice develop somatosensory dysfunction and axonal loss in the peripheral nerves

Glucose-responsive ATP-sensitive potassium channels (K(ATP)) are expressed in a variety of tissues including nervous systems. The depolarization of the membrane potential induced by glucose may lead to hyperexcitability of neurons and induce excitotoxicity. However, the roles of K(ATP) in the periph...

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Detalles Bibliográficos
Autores principales: Nakai-Shimoda, Hiromi, Himeno, Tatsuhito, Okawa, Tetsuji, Miura-Yura, Emiri, Sasajima, Sachiko, Kato, Makoto, Yamada, Yuichiro, Morishita, Yoshiaki, Tsunekawa, Shin, Kato, Yoshiro, Seino, Yusuke, Inoue, Rieko, Kondo, Masaki, Seino, Susumu, Naruse, Keiko, Kato, Koichi, Mizukami, Hiroki, Nakamura, Jiro, Kamiya, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719014/
https://www.ncbi.nlm.nih.gov/pubmed/35005553
http://dx.doi.org/10.1016/j.isci.2021.103609

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