Synthetic antibacterial discovery of symbah-1, a macrocyclic β-hairpin peptide antibiotic

The rapid development and spread of antibiotic resistance necessitate the development of novel strategies for antibiotic discovery. Symbah-1, a synthetic peptide antibiotic, was identified in a high-throughput antibacterial screen of random peptide sequences. Symbah-1 functions through membrane disr...

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Detalles Bibliográficos
Autores principales: Randall, Justin R., Davidson, Gillian, Fleeman, Renee M., Acosta, Santos A., Riddington, Ian M., Cole, T. Jeffrey, DuPai, Cory D., Davies, Bryan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719016/
https://www.ncbi.nlm.nih.gov/pubmed/35005555
http://dx.doi.org/10.1016/j.isci.2021.103611

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719016/
https://www.ncbi.nlm.nih.gov/pubmed/35005555
http://dx.doi.org/10.1016/j.isci.2021.103611

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