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Synthetic antibacterial discovery of symbah-1, a macrocyclic β-hairpin peptide antibiotic
The rapid development and spread of antibiotic resistance necessitate the development of novel strategies for antibiotic discovery. Symbah-1, a synthetic peptide antibiotic, was identified in a high-throughput antibacterial screen of random peptide sequences. Symbah-1 functions through membrane disr...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719016/ https://www.ncbi.nlm.nih.gov/pubmed/35005555 http://dx.doi.org/10.1016/j.isci.2021.103611 |