Epigenetic changes in human model KMT2A leukemias highlight early events during leukemogenesis

Chromosomal translocations involving the KMT2A gene are among the most common genetic alterations found in pediatric acute myeloid leukemias although the molecular mechanisms that initiate the disease remain incompletely defined. To elucidate these initiating events we used a human model system of a...

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Detalles Bibliográficos
Autores principales: Milan, Thomas, Celton, Magalie, Lagacé, Karine, Roques, Élodie, Safa-Tahar-Henni, Safia, Bresson, Eva, Bergeron, Anne, Hebert, Josée, Meshinchi, Soheil, Cellot, Sonia, Barabé, Frédéric, Wilhelm, Brian T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719083/
https://www.ncbi.nlm.nih.gov/pubmed/33375773
http://dx.doi.org/10.3324/haematol.2020.271619

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719083/
https://www.ncbi.nlm.nih.gov/pubmed/33375773
http://dx.doi.org/10.3324/haematol.2020.271619

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