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Post-translational polymodification of b1-tubulin regulates motor protein localization in platelet production and function

In specialized cells, the expression of specific tubulin isoforms and their subsequent post-translational modifications drive and coordinate unique morphologies and behaviors. The mechanisms by which b1-tubulin, the platelet and megakaryocyte (MK) lineage restricted tubulin isoform, drives platelet...

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Detalles Bibliográficos
Autores principales: Khan, Abdullah O., Slater, Alexandre, Maclachlan, Annabel, Nicolson, Phillip L.R., Pike, Jeremy A., Reyat, Jasmeet S., Yule, Jack, Stapley, Rachel, Rayes, Julie, Thomas, Steven G., Morgan, Neil V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719104/
https://www.ncbi.nlm.nih.gov/pubmed/33327716
http://dx.doi.org/10.3324/haematol.2020.270793