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Post-translational polymodification of b1-tubulin regulates motor protein localization in platelet production and function
In specialized cells, the expression of specific tubulin isoforms and their subsequent post-translational modifications drive and coordinate unique morphologies and behaviors. The mechanisms by which b1-tubulin, the platelet and megakaryocyte (MK) lineage restricted tubulin isoform, drives platelet...
Autores principales: | Khan, Abdullah O., Slater, Alexandre, Maclachlan, Annabel, Nicolson, Phillip L.R., Pike, Jeremy A., Reyat, Jasmeet S., Yule, Jack, Stapley, Rachel, Rayes, Julie, Thomas, Steven G., Morgan, Neil V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Fondazione Ferrata Storti
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719104/ https://www.ncbi.nlm.nih.gov/pubmed/33327716 http://dx.doi.org/10.3324/haematol.2020.270793 |
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