Mitochondrial Genome Study Identifies Association Between Primary Open-Angle Glaucoma and Variants in MT-CYB, MT-ND4 Genes and Haplogroups

Background and purpose: Primary open-angle glaucoma (POAG) is an optic neuropathy characterized by death of retinal ganglion cells and atrophy of the optic nerve head. The susceptibility of the optic nerve to damage has been shown to be mediated by mitochondrial dysfunction. In this study, we aimed...

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Detalles Bibliográficos
Autores principales: Lo Faro, Valeria, Nolte, Ilja M., Ten Brink, Jacoline B., Snieder, Harold, Jansonius, Nomdo M., Bergen, Arthur A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719162/
https://www.ncbi.nlm.nih.gov/pubmed/34976016
http://dx.doi.org/10.3389/fgene.2021.781189

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719162/
https://www.ncbi.nlm.nih.gov/pubmed/34976016
http://dx.doi.org/10.3389/fgene.2021.781189

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