Cargando…
Mitochondrial Genome Study Identifies Association Between Primary Open-Angle Glaucoma and Variants in MT-CYB, MT-ND4 Genes and Haplogroups
Background and purpose: Primary open-angle glaucoma (POAG) is an optic neuropathy characterized by death of retinal ganglion cells and atrophy of the optic nerve head. The susceptibility of the optic nerve to damage has been shown to be mediated by mitochondrial dysfunction. In this study, we aimed...
Autores principales: | Lo Faro, Valeria, Nolte, Ilja M., Ten Brink, Jacoline B., Snieder, Harold, Jansonius, Nomdo M., Bergen, Arthur A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719162/ https://www.ncbi.nlm.nih.gov/pubmed/34976016 http://dx.doi.org/10.3389/fgene.2021.781189 |
Ejemplares similares
-
Genome-wide CNV investigation suggests a role for cadherin, Wnt, and p53 pathways in primary open-angle glaucoma
por: Lo Faro, Valeria, et al.
Publicado: (2021) -
MT-CYB mutations in hypertrophic cardiomyopathy
por: Hagen, Christian M, et al.
Publicado: (2013) -
MT-CYB mutations in hypertrophic cardiomyopathy
por: Hagen, Christian M, et al.
Publicado: (2013) -
Genetic pre-screening for glaucoma in population-based epidemiology: protocol for a double-blind prospective screening study within Lifelines (EyeLife)
por: Neustaeter, Anna, et al.
Publicado: (2021) -
The m.15043G > A MT-CYB variant is not a pathogenic mtDNA variant
por: Alston, Charlotte L., et al.
Publicado: (2020)