X Chromosome Inactivation Pattern and Pregnancy Outcome of Female Carriers of Pathogenic Heterozygous X-Linked Deletions

Prenatal risk assessment of carriers of heterozygous X-linked deletion is a big challenge due to the phenotypic modification induced by X chromosome inactivation (XCI). Herein, we described four Chinese pedigrees with maternal-inherited X-deletions above 1 Mb. The pathogenic evaluation revealed that...

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Detalles Bibliográficos
Autores principales: Zhao, Yuanyin, Li, Jia, Dai, Limeng, Ma, Yongyi, Bai, Yun, Guo, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719196/
https://www.ncbi.nlm.nih.gov/pubmed/34976017
http://dx.doi.org/10.3389/fgene.2021.782629

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719196/
https://www.ncbi.nlm.nih.gov/pubmed/34976017
http://dx.doi.org/10.3389/fgene.2021.782629

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