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X Chromosome Inactivation Pattern and Pregnancy Outcome of Female Carriers of Pathogenic Heterozygous X-Linked Deletions

Prenatal risk assessment of carriers of heterozygous X-linked deletion is a big challenge due to the phenotypic modification induced by X chromosome inactivation (XCI). Herein, we described four Chinese pedigrees with maternal-inherited X-deletions above 1 Mb. The pathogenic evaluation revealed that...

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Detalles Bibliográficos
Autores principales:	Zhao, Yuanyin, Li, Jia, Dai, Limeng, Ma, Yongyi, Bai, Yun, Guo, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719196/ https://www.ncbi.nlm.nih.gov/pubmed/34976017 http://dx.doi.org/10.3389/fgene.2021.782629

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