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Reproducibility and replicability of high‐frequency, in‐home digital biomarkers in reducing sample sizes for clinical trials

INTRODUCTION: Reproducibility and replicability of results are rarely achieved for digital biomarkers analyses. We reproduced and replicated previously reported sample size estimates based on digital biomarker and neuropsychological test outcomes in a hypothetical 4‐year early‐phase Alzheimer's...

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Detalles Bibliográficos
Autores principales: Wu, Chao‐Yi, Beattie, Zachary, Mattek, Nora, Sharma, Nicole, Kaye, Jeffrey, Dodge, Hiroko H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719347/
https://www.ncbi.nlm.nih.gov/pubmed/35005204
http://dx.doi.org/10.1002/trc2.12220