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ACE2 can act as the secondary receptor in the FcγR-dependent ADE of SARS-CoV-2 infection
It is unknown whether antibody-mediated enhancement (ADE) contributes to the pathogenesis of COVID-19, and the conditions for ADE needs to be elucidated. We demonstrated that without inducing an ACE2-independent ADE on Raji cells, the neutralizing antibody CB6, a mouse anti-S1 serum and convalescent...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719361/ https://www.ncbi.nlm.nih.gov/pubmed/35005526 http://dx.doi.org/10.1016/j.isci.2021.103720 |