Cargando…

ACE2 can act as the secondary receptor in the FcγR-dependent ADE of SARS-CoV-2 infection

It is unknown whether antibody-mediated enhancement (ADE) contributes to the pathogenesis of COVID-19, and the conditions for ADE needs to be elucidated. We demonstrated that without inducing an ACE2-independent ADE on Raji cells, the neutralizing antibody CB6, a mouse anti-S1 serum and convalescent...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Zai, Deng, Tingting, Zhang, Yulian, Niu, Wenquan, Nie, Qiangqiang, Yang, Shengnan, Liu, Peipei, Pei, Pengfei, Chen, Long, Li, Haibo, Cao, Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719361/ https://www.ncbi.nlm.nih.gov/pubmed/35005526 http://dx.doi.org/10.1016/j.isci.2021.103720

Ejemplares similares

Antibody-dependent enhancement (ADE) of SARS-CoV-2 pseudoviral infection requires FcγRIIB and virus-antibody complex with bivalent interaction
por: Wang, Shuang, et al.
Publicado: (2022)

Susceptibility of the Elderly to SARS-CoV-2 Infection: ACE-2 Overexpression, Shedding, and Antibody-dependent Enhancement (ADE)
por: Peron, Jean Pierre Schatzmann, et al.
Publicado: (2020)

High Frequency of AdeA, AdeB and AdeC Genes among Acinetobacter baumannii Isolates
por: RANJBAR, Reza, et al.
Publicado: (2020)

SARS coronavirus has antibody-dependent enhancement (ADE) effect through the autologous antibodies against envelope spikes on Fcγ receptor expressing cells
por: Yeh, Chun-Sheng, et al.
Publicado: (2016)

AdeR-AdeS mutations & overexpression of the AdeABC efflux system in ciprofloxacin-resistant Acinetobacter baumannii clinical isolates
por: Lari, Abdolaziz Rastegar, et al.
Publicado: (2018)

Genetic dissection of a major haplotype associated with arthritis reveal FcγR2b and FcγR3 to act additively
por: Vaartjes, Daniëlle, et al.
Publicado: (2020)

The ADE Display Application
por: Solero, Almudena
Publicado: (2003)

Evaluation of Antibiotic Resistance and adeABC, adeR, adeS Efflux Pump Genes among Foodborne and Clinical Acinetobacter spp. in Türkiye
por: Terkuran, Mevhibe, et al.
Publicado: (2022)

Exact Anomalous Dimensions for N=2 ADE SCFTs
por: Oz, Y, et al.
Publicado: (2002)

Fc engineered ACE2-Fc is a potent multifunctional agent targeting SARS-CoV2
por: Wines, Bruce D., et al.
Publicado: (2022)

Ade2 Functions in the Drosophila Fat Body To Promote Sleep
por: Yurgel, Maria E., et al.
Publicado: (2018)

Corrigendum: Fc engineered ACE2-Fc is a potent multifunctional agent targeting SARS-CoV2
por: Wines, Bruce D., et al.
Publicado: (2023)

Fc Binding by FcγRIIa Is Essential for Cellular Activation by the Anti-FcγRIIa mAbs 8.26 and 8.2
por: Wines, Bruce D., et al.
Publicado: (2021)

Mutations from bat ACE2 orthologs markedly enhance ACE2-Fc neutralization of SARS-CoV-2
por: Mou, Huihui, et al.
Publicado: (2020)

Plasmapheresis, Anti-ACE2 and Anti-FcγRII Monoclonal Antibodies: A Possible Treatment for Severe Cases of COVID-19
por: Sedokani, Amin, et al.
Publicado: (2020)

Multivalent Fcγ-receptor engagement by a hexameric Fc-fusion protein triggers Fcγ-receptor internalisation and modulation of Fcγ-receptor functions
por: Qureshi, O. S., et al.
Publicado: (2017)

UDI'S, ADE y otros trucos /
por: Díaz Mata, Alfredo
Publicado: (1996)

ADE string vacua with discrete torsion
por: Kreuzer, Maximilian, et al.
Publicado: (1993)

Mutations derived from horseshoe bat ACE2 orthologs enhance ACE2-Fc neutralization of SARS-CoV-2
por: Mou, Huihui, et al.
Publicado: (2021)

Differential Binding of Carbapenems with the AdeABC Efflux Pump and Modulation of the Expression of AdeB Linked to Novel Mutations within Two-Component System AdeRS in Carbapenem-Resistant Acinetobacter baumannii
por: Roy, Subhasree, et al.
Publicado: (2022)

Engineered antibody Fc variant with selectively enhanced FcγRIIb binding over both FcγRIIa(R131) and FcγRIIa(H131)
por: Mimoto, F., et al.
Publicado: (2013)

Resistance to pentamidine is mediated by AdeAB, regulated by AdeRS, and influenced by growth conditions in Acinetobacter baumannii ATCC 17978
por: Adams, Felise G., et al.
Publicado: (2018)

Importance of the Side Chain at Position 296 of Antibody Fc in Interactions with FcγRIIIa and Other Fcγ Receptors
por: Isoda, Yuya, et al.
Publicado: (2015)

Ecto-ADP-ribosyltransferase ARTC2.1 functionally modulates FcγR1 and FcγR2B on murine microglia
por: Rissiek, Björn, et al.
Publicado: (2017)

Multivariate analysis of ecological data with ade4
por: Thioulouse, Jean, et al.
Publicado: (2018)

Challenges and opportunities integrating LLAMA into AdePT
por: Gruber, Bernhard Manfred, et al.
Publicado: (2023)

OneAPI for simulation: the AdePT project
por: Dosaru, Daniel-Florin
Publicado: (2021)

adeABC efflux gene in Acinetobacter baumannii
por: Xu, C., et al.
Publicado: (2019)

It is too soon to attribute ADE to COVID-19
por: Sharma, Anuj
Publicado: (2020)

Proteomic Characterization of PAMs with PRRSV-ADE Infection
por: Xu, Pengli, et al.
Publicado: (2022)

Inhibition of AdeB, AceI, and AmvA Efflux Pumps Restores Chlorhexidine and Benzalkonium Susceptibility in Acinetobacter baumannii ATCC 19606
por: Migliaccio, Antonella, et al.
Publicado: (2022)

Engineered ACE2-Fc counters murine lethal SARS-CoV-2 infection through direct neutralization and Fc-effector activities
por: Chen, Yaozong, et al.
Publicado: (2021)

Engineered ACE2-Fc counters murine lethal SARS-CoV-2 infection through direct neutralization and Fc-effector activities
por: Chen, Yaozong, et al.
Publicado: (2022)

Pathogenic autoantibodies to IFN-γ act through the impedance of receptor assembly and Fc-mediated response
por: Shih, Han-Po, et al.
Publicado: (2022)

Evolving understanding of antibody-dependent enhancement (ADE) of SARS-CoV-2
por: Yang, Yalong, et al.
Publicado: (2022)

Potent prophylactic and therapeutic efficacy of recombinant human ACE2-Fc against SARS-CoV-2 infection in vivo
por: Zhang, Zhaoyong, et al.
Publicado: (2021)

The Diverse Functions of the Ubiquitous Fcγ Receptors and Their Unique Constituent, FcRγ Subunit
por: Hamdan, Thamer A., et al.
Publicado: (2020)

Crystal structure of racemic cis-2-amino-1,2-diphenylethanol (ADE)
por: Fujii, Isao
Publicado: (2015)

Extrinsic stabilization of antiviral ACE2-Fc fusion proteins targeting SARS-CoV-2
por: Svilenov, Hristo L., et al.
Publicado: (2023)

In planta deglycosylation improves the SARS-CoV-2 neutralization activity of recombinant ACE2-Fc
por: Izadi, Shiva, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_faq6av3bhschd3u3v7rpp1sfkr