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A pharmacokinetic–pharmacodynamic model based on multi-organ-on-a-chip for drug–drug interaction studies
In drug discovery, the emergence of unexpected toxicity is often a problem resulting from a poor understanding of the pharmacokinetics of drug–drug interactions (DDI). Organ-on-a-chip (OoC) has been proposed as an in vitro model to evaluate drug efficacy and toxicity in pharmacology, but it has not...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
AIP Publishing LLC
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719524/ https://www.ncbi.nlm.nih.gov/pubmed/34992705 http://dx.doi.org/10.1063/5.0011545 |