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Heterogeneity of human anti-viral immunity shaped by virus, tissue, age, and sex

The persistence of anti-viral immunity is essential for protection and exhibits profound heterogeneity across individuals. Here, we elucidate the factors that shape maintenance and function of anti-viral T cell immunity in the body by comprehensive profiling of virus-specific T cells across blood, l...

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Detalles Bibliográficos
Autores principales: Poon, Maya M.L., Byington, Eve, Meng, Wenzhao, Kubota, Masaru, Matsumoto, Rei, Grifoni, Alba, Weiskopf, Daniela, Dogra, Pranay, Lam, Nora, Szabo, Peter A., Ural, Basak Burcu, Wells, Steven B., Rosenfeld, Aaron M., Brusko, Maigan A., Brusko, Todd M., Connors, Thomas J., Sette, Alessandro, Sims, Peter A., Prak, Eline T. Luning, Shen, Yufeng, Farber, Donna L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719595/
https://www.ncbi.nlm.nih.gov/pubmed/34852222
http://dx.doi.org/10.1016/j.celrep.2021.110071