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Heterogeneity of human anti-viral immunity shaped by virus, tissue, age, and sex
The persistence of anti-viral immunity is essential for protection and exhibits profound heterogeneity across individuals. Here, we elucidate the factors that shape maintenance and function of anti-viral T cell immunity in the body by comprehensive profiling of virus-specific T cells across blood, l...
Autores principales: | Poon, Maya M.L., Byington, Eve, Meng, Wenzhao, Kubota, Masaru, Matsumoto, Rei, Grifoni, Alba, Weiskopf, Daniela, Dogra, Pranay, Lam, Nora, Szabo, Peter A., Ural, Basak Burcu, Wells, Steven B., Rosenfeld, Aaron M., Brusko, Maigan A., Brusko, Todd M., Connors, Thomas J., Sette, Alessandro, Sims, Peter A., Prak, Eline T. Luning, Shen, Yufeng, Farber, Donna L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719595/ https://www.ncbi.nlm.nih.gov/pubmed/34852222 http://dx.doi.org/10.1016/j.celrep.2021.110071 |
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