Neuraminidase1 Inhibitor Protects Against Doxorubicin-Induced Cardiotoxicity via Suppressing Drp1-Dependent Mitophagy

Anthracyclines, such as doxorubicin (DOX), are among the effective chemotherapeutic drugs for various malignancies. However, their clinical use is limited by irreversible cardiotoxicity. This study sought to determine the role of neuraminidase 1 (NEU1) in DOX-induced cardiomyopathy and the potential...

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Detalles Bibliográficos
Autores principales: Qin, Yating, Lv, Chao, Zhang, Xinxin, Ruan, Weibin, Xu, Xiangyu, Chen, Chen, Ji, Xinyun, Lu, Li, Guo, Xiaomei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719652/
https://www.ncbi.nlm.nih.gov/pubmed/34977042
http://dx.doi.org/10.3389/fcell.2021.802502

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719652/
https://www.ncbi.nlm.nih.gov/pubmed/34977042
http://dx.doi.org/10.3389/fcell.2021.802502

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