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Transcriptomic profiling of adjuvant colorectal cancer identifies three key prognostic biological processes and a disease specific role for granzyme B

BACKGROUND: Colorectal cancer (CRC) is a leading cause of cancer-related deaths, with a 5% 5-year survival rate for metastatic disease, yet with limited therapeutic advancements due to insufficient understanding of and inability to accurately capture high-risk CRC patients who are most likely to rec...

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Detalles Bibliográficos
Autores principales: Daemen, Anneleen, Udyavar, Akshata R., Sandmann, Thomas, Li, Congfen, Bosch, Linda J. W., O’Gorman, William, Li, Yijin, Au-Yeung, Amelia, Takahashi, Chikara, Kabbarah, Omar, Bourgon, Richard, Hegde, Priti, Bais, Carlos, Das Thakur, Meghna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719661/
https://www.ncbi.nlm.nih.gov/pubmed/34972191
http://dx.doi.org/10.1371/journal.pone.0262198