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DHOK Exerts Anti-Cancer Effect Through Autophagy Inhibition in Colorectal Cancer

DHOK (14,15β-dihydroxyklaineanone) is a novel diterpene isolated from roots of Eurycoma longifolia Jack, a traditional herb widely applied in Southeast Asia. It is reported that DHOK has cytotoxic effect on cancer cells, but its anti-cancer mechanism has still been not clear. In our study, we first...

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Detalles Bibliográficos
Autores principales: Shu, Yuhan, Sun, Xin, Ye, Guiqin, Xu, Mengting, Wu, Zhipan, Wu, Caixia, Li, Shouxin, Tian, Jingkui, Han, Haote, Zhang, Jianbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719673/
https://www.ncbi.nlm.nih.gov/pubmed/34977014
http://dx.doi.org/10.3389/fcell.2021.760022