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Genome-wide gene expression noise in Escherichia coli is condition-dependent and determined by propagation of noise through the regulatory network

Although it is well appreciated that gene expression is inherently noisy and that transcriptional noise is encoded in a promoter’s sequence, little is known about the extent to which noise levels of individual promoters vary across growth conditions. Using flow cytometry, we here quantify transcript...

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Detalles Bibliográficos
Autores principales: Urchueguía, Arantxa, Galbusera, Luca, Chauvin, Dany, Bellement, Gwendoline, Julou, Thomas, van Nimwegen, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719677/
https://www.ncbi.nlm.nih.gov/pubmed/34919538
http://dx.doi.org/10.1371/journal.pbio.3001491