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Associations of FGF21 and GDF15 with mitochondrial dysfunction in children living with perinatally-acquired HIV: A cross-sectional evaluation of pediatric AIDS clinical trials group 219/219C

BACKGROUND: In persons living with HIV, mitochondrial disease (MD) is difficult to diagnose, as clinical signs are non-specific with inconsistent patterns. Fibroblast growth factor 21 (FGF21) and growth differentiation factor 15 (GDF15) are mitokines elevated in MD patients without HIV, and associat...

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Detalles Bibliográficos
Autores principales: Gojanovich, Greg S., Jacobson, Denise L., Broadwell, Carly, Karalius, Brad, Kirmse, Brian, Geffner, Mitchell E., Jao, Jennifer, Van Dyke, Russell B., McFarland, Elizabeth J., Silio, Margarita, Crain, Marilyn, Gerschenson, Mariana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719680/
https://www.ncbi.nlm.nih.gov/pubmed/34972147
http://dx.doi.org/10.1371/journal.pone.0261563