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Associations of FGF21 and GDF15 with mitochondrial dysfunction in children living with perinatally-acquired HIV: A cross-sectional evaluation of pediatric AIDS clinical trials group 219/219C
BACKGROUND: In persons living with HIV, mitochondrial disease (MD) is difficult to diagnose, as clinical signs are non-specific with inconsistent patterns. Fibroblast growth factor 21 (FGF21) and growth differentiation factor 15 (GDF15) are mitokines elevated in MD patients without HIV, and associat...
Autores principales: | Gojanovich, Greg S., Jacobson, Denise L., Broadwell, Carly, Karalius, Brad, Kirmse, Brian, Geffner, Mitchell E., Jao, Jennifer, Van Dyke, Russell B., McFarland, Elizabeth J., Silio, Margarita, Crain, Marilyn, Gerschenson, Mariana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719680/ https://www.ncbi.nlm.nih.gov/pubmed/34972147 http://dx.doi.org/10.1371/journal.pone.0261563 |
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