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Single-cell chromatin accessibility and lipid profiling reveals SCD1-dependent metabolic shift in adipocytes induced by bariatric surgery

Obesity promotes type 2 diabetes and cardiometabolic pathologies. Vertical sleeve gastrectomy (VSG) is used to treat obesity resulting in long-term weight loss and health improvements that precede weight loss; however, the mechanisms underlying the immediate benefits remain incompletely understood....

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Detalles Bibliográficos
Autores principales: Harlan, Blaine, Park, Hui Gyu, Spektor, Roman, Cummings, Bethany, Brenna, J. Thomas, Soloway, Paul D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719700/
https://www.ncbi.nlm.nih.gov/pubmed/34972124
http://dx.doi.org/10.1371/journal.pone.0261783