Cargando…
Biotechnological production optimization of argyrins – a potent immunomodulatory natural product class
Argyrins represent a family of cyclic octapeptides exhibiting promising immunomodulatory activity via inhibiting mitochondrial protein synthesis, which leads to reduced IL‐17 production by the T‐helper 17 cells. Argyrins are formed by a non‐ribosomal peptide synthetase (NRPS), originating from the m...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719831/ https://www.ncbi.nlm.nih.gov/pubmed/34724343 http://dx.doi.org/10.1111/1751-7915.13959 |