Common sequence motifs of nascent chains engage the ribosome surface and trigger factor

In the cell, the conformations of nascent polypeptide chains during translation are modulated by both the ribosome and its associated molecular chaperone, trigger factor. The specific interactions that underlie these modulations, however, are still not known in detail. Here, we combine protein engin...

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Detalles Bibliográficos
Autores principales: Deckert, Annika, Cassaignau, Anaïs M. E., Wang, Xiaolin, Włodarski, Tomasz, Chan, Sammy H. S., Waudby, Christopher A., Kirkpatrick, John P., Vendruscolo, Michele, Cabrita, Lisa D., Christodoulou, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719866/
https://www.ncbi.nlm.nih.gov/pubmed/34930833
http://dx.doi.org/10.1073/pnas.2103015118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719866/
https://www.ncbi.nlm.nih.gov/pubmed/34930833
http://dx.doi.org/10.1073/pnas.2103015118

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