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Common sequence motifs of nascent chains engage the ribosome surface and trigger factor
In the cell, the conformations of nascent polypeptide chains during translation are modulated by both the ribosome and its associated molecular chaperone, trigger factor. The specific interactions that underlie these modulations, however, are still not known in detail. Here, we combine protein engin...
Autores principales: | Deckert, Annika, Cassaignau, Anaïs M. E., Wang, Xiaolin, Włodarski, Tomasz, Chan, Sammy H. S., Waudby, Christopher A., Kirkpatrick, John P., Vendruscolo, Michele, Cabrita, Lisa D., Christodoulou, John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719866/ https://www.ncbi.nlm.nih.gov/pubmed/34930833 http://dx.doi.org/10.1073/pnas.2103015118 |
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