Defining the interactome of the human mitochondrial ribosome identifies SMIM4 and TMEM223 as respiratory chain assembly factors

Human mitochondria express a genome that encodes thirteen core subunits of the oxidative phosphorylation system (OXPHOS). These proteins insert into the inner membrane co-translationally. Therefore, mitochondrial ribosomes engage with the OXA1L-insertase and membrane-associated proteins, which suppo...

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Detalles Bibliográficos
Autores principales: Dennerlein, Sven, Poerschke, Sabine, Oeljeklaus, Silke, Wang, Cong, Richter-Dennerlein, Ricarda, Sattmann, Johannes, Bauermeister, Diana, Hanitsch, Elisa, Stoldt, Stefan, Langer, Thomas, Jakobs, Stefan, Warscheid, Bettina, Rehling, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719881/
https://www.ncbi.nlm.nih.gov/pubmed/34969438
http://dx.doi.org/10.7554/eLife.68213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719881/
https://www.ncbi.nlm.nih.gov/pubmed/34969438
http://dx.doi.org/10.7554/eLife.68213

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