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Single-cell transcriptome analysis identifies a unique tumor cell type producing multiple hormones in ectopic ACTH and CRH secreting pheochromocytoma

Ectopic Cushing’s syndrome due to ectopic ACTH&CRH-secreting by pheochromocytoma is extremely rare and can be fatal if not properly diagnosed. It remains unclear whether a unique cell type is responsible for multiple hormones secreting. In this work, we performed single-cell RNA sequencing to th...

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Detalles Bibliográficos
Autores principales: Zhang, Xuebin, Lian, Penghu, Su, Mingming, Ji, Zhigang, Deng, Jianhua, Zheng, Guoyang, Wang, Wenda, Ren, Xinyu, Jiang, Taijiao, Zhang, Peng, Li, Hanzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719890/
https://www.ncbi.nlm.nih.gov/pubmed/34905486
http://dx.doi.org/10.7554/eLife.68436