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Microglia Polarization from M1 toward M2 Phenotype Is Promoted by Astragalus Polysaccharides Mediated through Inhibition of miR-155 in Experimental Autoimmune Encephalomyelitis

Activated microglia is considered to be major mediators of the neuroinflammatory environment in demyelinating diseases of the central nervous system (CNS). Activated microglia are mainly polarized into M1 type, which plays a role in promoting inflammation and demyelinating. However, the proportion o...

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Detalles Bibliográficos
Autores principales: Liu, Xiaojun, Ma, Jinyun, Ding, Guiqing, Gong, Qianyi, Wang, Yuanhua, Yu, Hua, Cheng, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720009/
https://www.ncbi.nlm.nih.gov/pubmed/34976303
http://dx.doi.org/10.1155/2021/5753452