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SARS-CoV-2 infection enhances mitochondrial PTP complex activity to perturb cardiac energetics

SARS-CoV-2 is a newly identified coronavirus that causes the respiratory disease called coronavirus disease 2019 (COVID-19). With an urgent need for therapeutics, we lack a full understanding of the molecular basis of SARS-CoV-2-induced cellular damage and disease progression. Here, we conducted tra...

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Detalles Bibliográficos
Autores principales: Ramachandran, Karthik, Maity, Soumya, Muthukumar, Alagar R., Kandala, Soundarya, Tomar, Dhanendra, Abd El-Aziz, Tarek Mohamed, Allen, Cristel, Sun, Yuyang, Venkatesan, Manigandan, Madaris, Travis R., Chiem, Kevin, Truitt, Rachel, Vishnu, Neelanjan, Aune, Gregory, Anderson, Allen, Martinez-Sobrido, Luis, Yang, Wenli, Stockand, James D., Singh, Brij B., Srikantan, Subramanya, Reeves, W. Brian, Madesh, Muniswamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720045/
https://www.ncbi.nlm.nih.gov/pubmed/35005527
http://dx.doi.org/10.1016/j.isci.2021.103722