Plasma membrane perforation by GSDME during apoptosis-driven secondary necrosis

Secondary necrosis has long been perceived as an uncontrolled process resulting in total lysis of the apoptotic cell. Recently, it was shown that progression of apoptosis to secondary necrosis is regulated by Gasdermin E (GSDME), which requires activation by caspase-3. Although the contribution of G...

Descripción completa

Detalles Bibliográficos
Autores principales: De Schutter, Elke, Ramon, Jana, Pfeuty, Benjamin, De Tender, Caroline, Stremersch, Stephan, Raemdonck, Koen, de Beeck, Ken Op, Declercq, Wim, Riquet, Franck B., Braeckmans, Kevin, Vandenabeele, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720079/
https://www.ncbi.nlm.nih.gov/pubmed/34971436
http://dx.doi.org/10.1007/s00018-021-04078-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720079/
https://www.ncbi.nlm.nih.gov/pubmed/34971436
http://dx.doi.org/10.1007/s00018-021-04078-0

Ejemplares similares