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Production of galactosylated complex-type N-glycans in glycoengineered Saccharomyces cerevisiae

ABSTRACT: N-glycosylation is an important posttranslational modification affecting the properties and quality of therapeutic proteins. Glycoengineering in yeast aims to produce proteins carrying human-compatible glycosylation, enabling the production of therapeutic proteins in yeasts. In this work,...

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Detalles Bibliográficos
Autores principales: Piirainen, Mari A., Salminen, Heidi, Frey, Alexander D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720083/
https://www.ncbi.nlm.nih.gov/pubmed/34910238
http://dx.doi.org/10.1007/s00253-021-11727-8