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Biased TCR gene usage in citrullinated Tenascin C specific T-cells in rheumatoid arthritis

We aimed to search for common features in the autoreactive T cell receptor (TCR) repertoire in patients with rheumatoid arthritis (RA), focusing on the newly identified candidate antigen citrullinated Tenascin C (cit-TNC). Mononuclear cells from peripheral blood or synovial fluid of eight RA-patient...

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Detalles Bibliográficos
Autores principales: Sharma, Ravi K., Boddul, Sanjay V., Yoosuf, Niyaz, Turcinov, Sara, Dubnovitsky, Anatoly, Kozhukh, Genadiy, Wermeling, Fredrik, Kwok, William W., Klareskog, Lars, Malmström, Vivianne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720095/
https://www.ncbi.nlm.nih.gov/pubmed/34972837
http://dx.doi.org/10.1038/s41598-021-04291-8