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Impact on NK cell functions of acute versus chronic exposure to extracellular vesicle‐associated MICA: Dual role in cancer immunosurveillance

Natural killer (NK) cells are innate cytotoxic lymphocytes that play a key role in cancer immunosurveillance thanks to their ability to recognize and kill cancer cells. NKG2D is an activating receptor that binds to MIC and ULBP molecules typically induced on damaged, transformed or infected cells. T...

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Detalles Bibliográficos
Autores principales: Vulpis, Elisabetta, Loconte, Luisa, Peri, Agnese, Molfetta, Rosa, Caracciolo, Giulio, Masuelli, Laura, Tomaipitinca, Luana, Peruzzi, Giovanna, Petillo, Sara, Petrucci, Maria Teresa, Fazio, Francesca, Simonelli, Lucilla, Fionda, Cinzia, Soriani, Alessandra, Cerboni, Cristina, Cippitelli, Marco, Paolini, Rossella, Bernardini, Giovanni, Palmieri, Gabriella, Santoni, Angela, Zingoni, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720178/
https://www.ncbi.nlm.nih.gov/pubmed/34973063
http://dx.doi.org/10.1002/jev2.12176