YTHDC2 is essential for pachytene progression and prevents aberrant microtubule-driven telomere clustering in male meiosis

Mechanisms driving the prolonged meiotic prophase I in mammals are poorly understood. RNA helicase YTHDC2 is critical for mitosis to meiosis transition. However, YTHDC2 is highly expressed in pachytene cells. Here we identify an essential role for YTHDC2 in meiotic progression. Specifically, YTHDC2...

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Detalles Bibliográficos
Autores principales: Liu, Rong, Kasowitz, Seth D., Homolka, David, Leu, N. Adrian, Shaked, Jordan T., Ruthel, Gordon, Jain, Devanshi, Lin, Huijuan, Keeney, Scott, Luo, Mengcheng, Pillai, Ramesh S., Wang, P. Jeremy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720241/
https://www.ncbi.nlm.nih.gov/pubmed/34910909
http://dx.doi.org/10.1016/j.celrep.2021.110110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720241/
https://www.ncbi.nlm.nih.gov/pubmed/34910909
http://dx.doi.org/10.1016/j.celrep.2021.110110

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