Naive human B cells engage the receptor binding domain of SARS-CoV-2, variants of concern, and related sarbecoviruses

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Initial exposure to a pathogen elicits an adaptive immune response to control and eradicate the threat. Interrogating the abundance and specificity of the naive B cell repertoire drives understanding of how to mount protective responses. Here, we isolated naive B cells from 8 seronegative human dono...

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Detalles Bibliográficos
Autores principales: Feldman, Jared, Bals, Julia, Altomare, Clara G., St. Denis, Kerri, Lam, Evan C., Hauser, Blake M., Ronsard, Larance, Sangesland, Maya, Moreno, Thalia Bracamonte, Okonkwo, Vintus, Hartojo, Nathania, Balazs, Alejandro B., Bajic, Goran, Lingwood, Daniel, Schmidt, Aaron G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720485/
https://www.ncbi.nlm.nih.gov/pubmed/34648356
http://dx.doi.org/10.1126/sciimmunol.abl5842

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720485/
https://www.ncbi.nlm.nih.gov/pubmed/34648356
http://dx.doi.org/10.1126/sciimmunol.abl5842

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